6.7 methylenedioxy-3.4-dihydroisoquinolin.



UNITED STATES PATENTYOFFICE.

HERMAN DECKER,- OF HANOVER, GERMANY, ASSIGNOR T FARBENFABRIKEN VORM. FRIEDB. BAYER & (30. OF ELBERFELD, GERMANY, A CORPORATION OF GERMANY.

8.'Y-METHYIiENElDIOXY-B.4-DIHYDROISOQUINOLIN.

Specification of Letters intent. Patente Application filed April-11, 1911. Serial No. 620,429.

1,010,593. No Drawing.

I have found that the hitherto unknown 6.7-methylenedioxy 3.4 dihydroisoquinolin can be obtained by treating the formyl compound of homopiperonylamin with hosphorous pentoxid. The reaction pro ably proceeds in accordance with the following equation:

To all whom it mdy concern;

Be it knomithat I, HER AN Dncmydoctor of philosophy, chemist, citizen of the Germarfllmpire, residing at Hanover, Gernanv, have invented new and useful Improvements in 6.7-Methylenedioxy-3.4-dihy;

droisoquinolin, of which the following is a cH' \CH, EH, kn shownt 03 H specification.

I O p cm N 4 It is a white powdermelting at 90-91" C. soluble in alcohol and ether, insoluble in ligroin. Its solutions show a blue fluor- I claiin v The herein described 6.7 -m'ethylened1oxy- 3.4-dih droisoquinolin which is a white powd Dec. 5', 1911.

escence. By heatin it withICH (1 moleder me ting at 90 9l 0., soluble inalcohol cule) it is converte into the iodohydrete of and ether, being insoluble in ligrom; and hydrastinin melting at 234 C. v being converted by treatinentwith IQH In order to illustrate the new process more into the lodohydrate of hydrestinm melting 7 fully the following example is given, the at 234 (1., substantially as described. parts being by weight :10 parts of the In testimony whereof I have hereunto set formyl compound of homopiperon lamin my hand in the presence of two subscriblng (needles M. P. til-62 U.) are disso ved in witnesses. 7 5 parts of toluene and heated with parts of P 0 to 100 C. The toluene is distilled HERMAN DECKER. [L.s.] off, the residue is poured into water and the new product is precipitated with NaOH. Witnesses:

The formyl com ound of homopi eronyl- ERNEST C. Osmznonrznn, amin is obtained y treating 3.4- ioxy-m- M.

phenylethylemin with formic acid. 

